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Friday 29 Jul 2016

Rett’s Syndrome


Rett’s Syndrome is an Autism Spectrum Disorder classified by loss of social interest, receptive and expressive language, and motor skills. Below is the diagnostic criteria.

DSM-IV Criteria:

The essential feature of Rett’s Disorder is the development of multiple specific deficits following a period of normal functioning after birth. There is a loss of previously acquired purposeful hand skills before subsequent development of characteristic hand movement resembling hand wringing or hand washing. Interest in the social environment diminishes in the first few years after the onset of the disorder. There is also significant impairment in expressive and receptive language development with severe psychomotor retardation.

A. All of the following:

  • Apparently normal prenatal and perinatal development
  • Apparently normal psychomotor development through the first 5 months after birth
  • Normal head circumference at birth

B. Onset of all of the following after the period of normal development:

  • Deceleration of head growth between ages 5 and 48 months
  • Loss of previously acquired purposeful hand skills between ages 5 and 30 months with the subsequent development of stereotyped hand movements (e.g., hand-wringing or hand washing)
  • Loss of social engagement early in the course (although often social interaction develops later)
  • Appearance of poorly coordinated gait or trunk movements
  • Severely impaired expressive and receptive language development with severe psychomotor retardation

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